Gout is caused by the increase in the amount of uric acid in the blood. Uric acid is normally removed from the body through the urine, however if it is not excreted it can form crystals, which irritate body tissues like the lining of joints. This will in turn cause inflammation and pain, which is often quite severe.

The relief of pain is remarkable with some of the anti-inflammatory medicines also called NSAIDS or non-steroidal anti-inflammatory medications. The typical example is indomethacin or ibuprofen. Applying local ice or heat may sometimes help as well as keeping the joint without moving or bumping into objects.

Colchicine is typically used if the first line medications like NSAID