Most women who are estrogen-dominant prefer to use natural progesterone to balance estrogen. Excess estrogen can cause severe problems such as breast cysts and cancer. However, natural progesterone can also produce some side effects since it is a synthetically produced product. Natural progesterone produces some side effects if too much is taken and has to be used with care.

Since progesterone is a fat-soluble hormone, it can result in the user gaining weight after using the cream for a long time. Since this happens in small quantities, initial use might not produce any such result. This is because excessive use of progesterone cream results in disruption of other hormones in the body.

It is suggested to reduce the usage of the cream after the adrenal hormones normalize. A doctor