Central sleep apnea is a rare condition characterized by a cessation or decrease in breathing during sleep due to problem with signals from the brain that control breathing.

The symptoms of central sleep apnea are loud snoring, hypersomnolence (excessive daytime sleepiness), and restless sleep. The problem of excessive daytime sleepiness (especially while driving, working or talking) develops slowly over years and is noticeable by friends and colleagues. Hypersomnolence and neurocognitive disturbances stand as a cause for automobile or work-related accidents in sleep apnea patients.

Other symptoms of central sleep apnea include choking or gasping during sleep, unrefreshing sleep, morning headaches, daytime fatigue, personality changes, memory impairment, impaired concentration, poor judgment, mood disturbances, recent weight gain, polyurea, and impotence.

The hypoxic and hypercapnic drives can be impaired by brain stem lesions or by exposure to recurrent hypoxia and hypercapnia and result in central sleep apnea. The stimulus to breathe instead from the cortex and reticular activating system is lost during sleep and the patient stops breathing, the so-called