Prostate Cancer Cells Killed by Capsicum

According to a study published in the March 2006 issue of Cancer Research, capsicum helps halt prostrate cancer spread. Capsaicin probably has a certain positive consequence, the study concluded. Most important seems to be blocking NF-kappa Beta effect, a molecular mechanism that promotes cancer cell growth.

Capsicum it's a pepper and capsaicin is the ingredient that makes them hot.

The study concluded that in prostate cancer cells whose growth is testosterone dependent, capsaicin influenced more prostate cancer cells to freeze in a non-proliferative status, called G0/G1. The research team also found that prostate cancer cells that are androgen independent reacted to capsaicin in a similar manner.

Based on team's explanation, capsaicin lowers the amount of androgen receptor that the tumor cells produced, but did not obstruct normal movement of androgen receptor into the nucleus of the cancer cells where the steroid receptor works to regulate androgen target genes such as PSA (prostate specific antigen). The same source claims that capsaicin had a significant anti-proliferative action on human prostate cancer cells in culture. It also significant slowed the development of prostate tumors created by those human cell lines grown in mouse models.

In addition, capsaicin also was effective against leukemia, and might be effective in slowing or preventing the growth of other cancers as well.

It may be possible that capsaicin to be extracted from hot chillies and have it soon as a drug. However, people should take care not to increase the chillies intake as that has been associated with stomach cancers.

Valerian D is a freelance writer specialized in health issues affecting men such as prostate cancer treatment