Many antidepressants can cause weight gain. Studies show that antidepressants can cause unnesscesary weight gain an average of 10-15%. I gained over 35 pounds after taking antidepressants.

Monoamine oxidase inhibitors (MAOIs) are effective medications for some people with depression who may not respond to other antidepressants. They also work for patients with panic disorder and bipolar disorder. The MAOIs approved to treat depression are phenelzine (Nardil), tranylcypromine (Parnate), and isocarboxazid (Marplan). But these drugs also show can cause unncessary weight gain. On average, patients gain between 10-15% in weight.

Also, because substances in certain foods, beverages, and medications can cause dangerous interactions when combined with MAOIs, people who use them must adhere to some dietary restrictions. This has deterred many clinicians from prescribing these medications, but they are very safe and effective when used as directed.

People who use MAOIs need to avoid taking decongestants and consuming certain foods that contain high levels of the amino acid tyramine. This includes many cheeses, wines, and pickles. The interaction of tyramine with MAOIs can bring on a sharp increase in blood pressure that can lead to a stroke. Your doctor should provide you with a complete list of prohibited foods. Carry this list with you at all times. Other antidepressants require no food restrictions.

The FDA has approved the first ever medical device for depression. It has none of the side effects of drugs and has no drugs interactions or dietary restrictions.

I was implanted with the device in 2001 and by the way I have lost that extra 35 pounds, live depression-free and do not have to take any antidepressants. Thank goodness!

Charles Donovan was a patient in the FDA investigational trial of vagus nerve stimulation as a treatment for chronic or recurrent treatment-resistant depression. He was implanted with the vagus nerve stimulator in April of 2001. He chronicles his journey from the grips of depression thanks to vagus nerve stimulation therapy in his book:

Out of the Black Hole: The Patient's Guide to Vagus Nerve Stimulation and Depression

His all inclusive book prepares depression sufferers to make an informed decision about this ninety-minute out-patient procedure. It is a "must read" before you discuss this treatment with your psychiatrist. A prescription for the procedure is required from an M.D. and it is covered by most insurance plans.

He is the founder of the http://www.VagusNerveStimulation.com Web Site and Bulletin.