Time Line of the Development of GlycoBiology and GlycoNutritionals

1880s - Characterization of monosaccharides by Emil Fischer.

1952 - Fresh, not aged, Aloe gel heals radiation burns on rabbits (Clarence C. Lushbaugh, Cancer 1953 vol. 6)

1970 - 500 glycobiology papers published.

1976 - Research paper identifies the 8 sugars found in biological glycoproteins and glycolipids.

1980 - 1500 glycobiology papers published.

1990 - 4000 glycobiology papers published.

1990 - Journal of Glycobiology started by Oxford University.

1990 - "Capitalizing on Carbohydrates" by John Hodgson in BioTechnology, Vol 8 Feb. 1990 discussing cell surfaces containing carbohydrates involved in intercellular communication and essential for immune function.

1992 - Active component in Aloe gel is stabilized.

1995 - Nature: cell surface sugars necessary for recognition and immune function.

1996 - Harper's Biochemistry, Murray et al.: chapter on glycoproteins focuses on the 8 necessary sugars used in glycoproteins and glycolipids for cellular communication.

1998 - Integrative Physiological and Behavioral Science, January, vol. 33, #1, Articles on ADHD & Fibromyalgia

1998 - Acta Anatomica: special March issue on glycoscience; emphasizes that information content of biological sugar combinations exceeds that of the DNA code.

1998 - Healthy humans given radiologically labeled galactose, mannose and glucose incorporate all three directly into glycoproteins, proving that the body uses the different sugars as nutrients directly from the diet, instead of manufacturing them all from glucose alone. Biochimie