Shocking Truths About Pescription Anti-Inflammatory Drugs!
What are NSAIDs?
NSAID stands for Nonsteroidal anti-inflammatory drugs. These
drugs are popular prescriptions that are taken to relieve the
inflammation associated with arthritis, bursitis, tendonitis,
etc. NSAIDs decrease inflammation by hindering the production of
prostaglandins; a natural chemical associated with body
inflammation.
What are the potential negative side effects of NSAIDs?
Approximately 10-50% of patients suffer with gastrointestinal
issues such as abdominal pain, diarrhea, bloating, heartburn,
and upset stomach. Furthermore, 15% develop ulcers after
long-term use.
What is a Cox-1 enzyme?
Cyclooxygenase-1 (Cox-1) is an enzyme that is present at sites
of inflammation as well as in the stomach. The Cox-1 enzyme of
the stomach produces prostaglandins, chemical messenger. These
prostaglandins protect the lining of the stomach from the acids
that it contains. When Cox-1 enzymes are inhibited, inflammation
is reduced; however, the integrity of the stomach lining is
compromised. This reduction to the stomach leads to ulcers and
other gastrointestinal issues.
What is a Cox-2 enzyme?
Cyclooxygenase-2 (Cox-2) produces prostaglandins also but solely
at the sites of inflammation. Therefore, hindering these enzymes
reduces inflammation.
What is a Cox-2 Inhibitor?
Cox-2 inhibitors are a new class of nonsteroidal
anti-inflammatory drugs (NSAIDs). Because they selectively block
the Cox-2 enzyme and not the Cox-1 enzyme, these drugs are
uniquely different from traditional NSAIDs.
Why were Cox-2 Inhibitors created?
Cox-2 Inhibitors were created to reduce inflammation without
compromising the stomach lining. Therefore, inflammation
sufferers will achieve relief without being at risk for ulcers.
What is the danger surrounding Cox-2 Inhibitors? (i.e.,
Celebrex, Vioxx, and Bextra)
Although in theory Cox-2 Inhibitors are a great solution, they
have some definite health considerations you need to know before
you take them. Cox-2 inhibitors have been manufactured in one
set dosage. The only available dosage is at such a high level
there is an extremely high risk for strokes and heart attacks.
Without the option for healthcare professionals to individualize
prescriptions for their patients, all patients are receiving the
same amount regardless of height, weight, sex, medical history
etc. The negative risk have been so great, the FDA formed an
Advisory Committee consisting of 32 experts who agree that these
Cox-2 Inhibitors cause too high a risk for strokes and heart
attacks. They recommend that healthcare providers to be very
cautious as to which patients they prescribe Cox-2 despite the
pharmaceutical companies flashy advertising.
Are there natural alternatives to Cox-2 Inhibitors?
There are many viable natural options available for individuals
suffering from inflammatory diseases such as arthritis and
overuse type conditions such as tendonitis and bursitis.
Specifically, there is an ingredient called Nexrutine offered by
Next Pharmaceuticals that works on the Cox 2 enzyme without
platelet aggregation or risk of cardiovascular health. Nexrutine
taken by itself is a very good natural pain reliever. Optimal
Therapeutics produces a Nexrutine ingredient based product
called Phosoplex. The product promotes healthy joint function
and also helps to alleviate pain and swelling. This cumulative
effect allows for the repair of damaged joints. What makes the
product so effective? In addition to Nexrutine, Phosoplex
contains a synergistic blend of powerful ingredients such as
Hyaluronic Acid, MSM, Glucosamine, BioCell Collagen II. Overall
Phosoplex is as effective as any other natural joint pain
reliever on the market today.
Based on current research and recent problems with
pharmaceutical pain relieving drugs, natural alternative
ingredients like Nexrutine and natural formulas like Phosoplex
are the future for safe and effective pain management.