High Altitude Health Problems
Article on High Altitude Health Tips :
Human body, either working or exposed to working at high
altitude can be hazardous.
The information provided here is designed for educational use
only and is not a substitute for specific training or experience.
What is High Altitude?: -----------------------
Altitude is defined on the following scale High (8,000 - 12,000
feet [2,438 - 3,658 meters]), Very High (12,000 - 18,000 feet
[3,658 - 5,487 meters]), and Extremely High (18,000+ feet
[5,500+ meters]). Since few people have been to such altitudes,
it is hard to know who may be affected. There are no specific
factors such as age, sex, or physical condition that correlate
with susceptibility to altitude sickness. Some people get it and
some people don't, and some people are more susceptible than
others. Most people can go up to 8,000 feet (2,438 meters) with
minimal effect. If you haven't been to high altitude before,
it's important to be cautious. If you have been at that altitude
before with no problem, you can probably return to that altitude
without problems as long as you are properly acclimatized.
What Causes Altitude Illnesses: -------------------------------
The concentration of oxygen at sea level is about 21% and the
barometric pressure averages 760 mmHg. As altitude increases,
the concentration remains the same but the number of oxygen
molecules per breath is reduced. At 12,000 feet (3,658 meters)
the barometric pressure is only 483 mmHg, so there are roughly
40% fewer oxygen molecules per breath. In order to properly
oxygenate the body, your breathing rate (even while at rest) has
to increase. This extra ventilation increases the oxygen content
in the blood, but not to sea level concentrations. Since the
amount of oxygen required for activity is the same, the body
must adjust to having less oxygen. In addition, for reasons not
entirely understood, high altitude and lower air pressure causes
fluid to leak from the capillaries which can cause fluid
build-up in both the lungs and the brain. Continuing to higher
altitudes without proper acclimatization can lead to potentially
serious, even life-threatening illnesses.
Acclimatization: -----------------
The major cause of altitude illnesses is going too high too
fast. Given time, your body can adapt to the decrease in oxygen
molecules at a specific altitude. This process is known as
acclimatization and generally takes 1-3 days at that altitude.
For example, if you hike to 10,000 feet (3,048 meters), and
spend several days at that altitude, your body acclimatizes to
10,000 feet (3,048 meters). If you climb to 12,000 feet (3,658
meters), your body has to acclimatize once again. A number of
changes take place in the body to allow it to operate with
decreased oxygen. The depth of respiration increases. Pressure
in pulmonary arteries is increased, "forcing" blood into
portions of the lung which are normally not used during sea
level breathing. The body produces more red blood cells to carry
oxygen, The body produces more of a particular enzyme that
facilitates the release of oxygen from hemoglobin to the body
tissues.
Prevention of Altitude Illnesses:
---------------------------------
Prevention of altitude illnesses falls into two categories,
proper acclimatization and preventive medications. Below are a
few basic guidelines for proper acclimatization.
If possible, don't fly or drive to high altitude. Start below
10,000 feet (3,048 meters) and walk up. If you do fly or drive,
do not over-exert yourself or move higher for the first 24
hours. If you go above 10,000 feet (3,048 meters), only increase
your altitude by 1,000 feet (305 meters) per day and for every
3,000 feet (915 meters) of elevation gained, take a rest day.
"Climb High and sleep low." This is the maxim used by climbers.
You can climb more than 1,000 feet (305 meters) in a day as long
as you come back down and sleep at a lower altitude. If you
begin to show symptoms of moderate altitude illness, don't go
higher until symptoms decrease (& Don't go up until symptoms go
down").
If symptoms increase, go down, down, down! Keep in mind that
different people will acclimatize at different rates. Make sure
all of your party is properly acclimatized before going
higher.Stay properly hydrated. Acclimatization is often
accompanied by fluid loss, so you need to drink lots of fluids
to remain properly hydrated (at least 3-4 quarts per day). Urine
output should be copious and clear.
Take it easy; don't over-exert yourself when you first get up to
altitude. Light activity during the day is better than sleeping
because respiration decreases during sleep, exacerbating the
symptoms. Avoid tobacco and alcohol and other depressant drugs
including, barbiturates, tranquilizers, and sleeping pills.
These depressants further decrease the respiratory drive during
sleep resulting in a worsening of the symptoms.
Eat a high carbohydrate diet (more than 70% of your calories
from carbohydrates) while at altitude. The acclimatization
process is inhibited by dehydration, over-exertion, and alcohol
and other depressant drugs.
Preventive Medications: -----------------------
Diamox (Acetazolamide) allows you to breathe faster so that you
metabolize more oxygen, thereby minimizing the symptoms caused
by poor oxygenation. This is especially helpful at night when
respiratory drive is decreased. Since it takes a while for
Diamox to have an effect, it is advisable to start taking it 24
hours before you go to altitude and continue for at least five
days at higher altitude. The recommendation of the Himalayan
Rescue Association Medical Clinic is 125 mg. twice a day
(morning and night). (The standard dose was 250 mg., but their
research showed no difference for most people with the lower
dose, although some individuals may need 250 mg.) Possible side
effects include tingling of the lips and finger tips, blurring
of vision, and alteration of taste. These side effects may be
reduced with the 125 mg. dose. Side effects subside when the
drug is stopped. Contact your physician for a prescription.
Since Diamox is a sulfonamide drug, people who are allergic to
sulfa drugs should not take Diamox. Diamox has also been known
to cause severe allergic reactions to people with no previous
history of Diamox or sulfa allergies. Frank Hubbell of SOLO
recommends a trial course of the drug before going to a remote
location where a severe allergic reaction could prove difficult
to treat. Dexamethasone (a steroid)
Acute Mountain Sickness (AMS): -----------------------------
AMS is common at high altitudes. At elevations over 10,000 feet
(3,048 meters), 75% of people will have mild symptoms. The
occurrence of AMS is dependent upon the elevation, the rate of
ascent, and individual susceptibility. Many people ill
experience mild AMS during the acclimatization process. Symptoms
usually start 12-24 hours after arrival at altitude and begin to
decrease in severity about the third day. The symptoms of Mild
AMS are headache, dizziness, fatigue, shortness of breath, loss
of appetite, nausea, disturbed sleep, and a general feeling of
malaise. Symptoms tend to be worse at night and when respiratory
drive is decreased. Mild AMS does not interfere with normal
activity and symptoms generally subside within 2-4 days as the
body acclimatizes. As long as symptoms are mild, and only a
nuisance, ascent can continue at a moderate rate. When hiking,
it is essential that you communicate any symptoms of illness
immediately to others on your trip. AMS is considered to be a
neurological problem caused by changes in the central nervous
system. It is basically a mild form of High Altitude Cerebral
Edema (see below).
Basic Treatment of AMS: -----------------------
The only cure is either acclimatization or descent. Symptoms of
Mild AMS can be treated with pain medications for headache and
Diamox. Both help to reduce the severity of the symptoms, but
remember, reducing the symptoms is not curing the problem.
Diamox allows you to breathe faster so that you metabolize more
oxygen, thereby minimizing the symptoms caused by poor
oxygenation. This is especially helpful at night when
respiratory drive is decreased. Since it takes a while for
Diamox to have an effect, it is advisable to start taking it 24
hours before you go to altitude and continue for at least five
days at higher altitude. The recommendation of the Himalayan
Rescue Association Medical Clinic is 125 mg. twice a day
(morning and night). (The standard dose was 250 mg., but their
research showed no difference for most people with the lower
dose, although some individuals may need 250 mg.) Possible side
effects include tingling of the lips and finger tips, blurring
of vision, and alteration of taste. These side effects may be
reduced with the 125 mg. dose. Side effects subside when the
drug is stopped. Contact your physician for a prescription.
Since Diamox is a sulfonamide drug, people who are allergic to
sulfa drugs should not take Diamox. Diamox has also been known
to cause severe allergic reactions to people with no previous
history of Diamox or sulfa allergies. Frank Hubbell of SOLO in
New Hampshire recommends a trial course of the drug before going
to a remote location where a severe allergic reaction could
prove difficult to treat.
Moderate AMS: --------------
Moderate AMS includes severe headache that is not relieved by
medication, nausea and vomiting, increasing weakness and
fatigue, shortness of breath, and decreased coordination
(ataxia). Normal activity is difficult, although the person may
still be able to walk on their own. At this stage, only advanced
medications or descent can reverse the problem. Descending even
a few hundred feet (70-100 meters) may help and definite
improvement will be seen in descents of 1,000-2,000 feet
(305-610 meters). Twenty-four hours at the lower altitude will
result in significant improvements. The person should remain at
lower altitude until symptoms have subsided (up to 3 days). At
this point, the person has become acclimatized to that altitude
and can begin ascending again. The best test for moderate AMS is
to have the person "walk a straight line" heel to toe. Just like
a sobriety test, a person with ataxia will be unable to walk a
straight line. This is a clear indication that immediate descent
is required. It is important to get the person to descend before
the ataxia reaches the point where they cannot walk on their own
(which would necessitate a litter evacuation).
Severe AMS: -----------
Severe AMS presents as an increase in the severity of the
aforementioned symptoms, including shortness of breath at rest,
inability to walk, decreasing mental status, and fluid buildup
in the lungs. Severe AMS requires immediate descent to lower
altitudes (2,000 - 4,000 feet [610-1,220 meters]).
There are two other severe forms of altitude illness, High
Altitude Cerebral Edema (HACE) and High Altitude Pulmonary Edema
(HAPE). Both of these happen less frequently, especially to
those who are properly acclimatized. When they do occur, it is
usually with people going too high too fast or going very high
and staying there. The lack of oxygen results in leakage of
fluid through the capillary walls into either the lungs or the
brain.
High Altitude Pulmonary Edema (HAPE):
------------------------------------
HAPE results from fluid buildup in the lungs. The fluid in the
lungs prevents effective oxygen exchange. As the condition
becomes more severe, the level of oxygen in the bloodstream
decreases, and this can lead to cyanosis, impaired cerebral
function, and death. Symptoms include shortness of breath even
at rest.
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