Tylenol Most Common Cause of Liver Failure
Acetaminophen poisoning is now the most common cause of acute
liver failure in the United States. Attempted suicides account
for many cases, but almost half are the result of unintentional
overdose.
Unintentional Overdose Worse Than Intentional
Some 36 percent of Americans take acetaminophen at least once a
month, making it the most widely used pain reliever in the
United States. Taking more than the recommended dose, however,
can lead to fatal liver injury.
And those who had unintentionally taken overdoses usually have
even worse outcomes than those who has done so intentionally,
since unintentional overdoses are usually not recognized as such
immediately.
Cases Nearly Doubled Over Five Years
Researchers examined the case histories of almost 700
liver-failure patients over a six-year period. They found
that:- Cases of acute liver failure blamed on
acetaminophen use rose sharply from 28 percent in 1998 to 51
percent five years later.
- More patients overdosed
unintentionally on acetaminophen (48 percent) than did so
intentionally (44 percent)
- Sixty-three percent who
accidentally overdosed used a prescription acetaminophen
compound while 38 percent had been taking two acetaminophen meds
at the same time.
- Some patients had been taking less than 4
grams of acetaminophen daily before their livers
failed.
As Little as 7.5 Grams Per Day
The data suggests that consistent use of as little as 7.5 grams
of acetaminophen a day may be hazardous. Rather than resulting
in chronic illness, acetaminophen injury has a threshold of
safety that, when exceeded, can have immediate and devastating
results.
Hepatology December 2005; 42(6): 1364-1372EurekAlert November
29, 2005
Dr. Mercola's Comment:You probably already knew that acute
liver failure is one of the more health-harming side effects of
acetaminophen. Experts believe acetaminophen causes its damage
by depleting your body of glutathione. If you keep your
glutathione levels up, the damage from acetaminophen may be
largely preventable.
Even conventional medicine recognizes this, as anyone who
overdoses on it receives large doses of N-acetyl cysteine (NAC)
in the emergency room. NAC is a precursor of glutathione and
helps restore this necessary and important bionutrient when
Tylenol suppresses it.
Pain is an important "clue" that your body provides you and it
is typically seeking to warn you to correct the underlying
disorder. So the best and foremost action you can take is to
seek to identify the cause of your pain.
If you are unable to address the cause immediately, such as an
accident, then you will certainly want to consider using the
amazing tool of EFT. Last month I ran a story of how you can use
it for burns and muscle injuries. But you could use it for just
about any type of pain.
Tylenol is effective fordiscomfort due to inflammatory and
non-inflammatory pain. If you want to treat any inflammatory
pain without harming your health, you'll want to review my
recent piece on seven safe and effective treatments, none of
which have anything to do with a drug but are useful for
inflammatory-type pain:
Ginger: This herb is anti-inflammatory and offers pain relief
and stomach-settling properties. Fresh ginger works well steeped
in boiling water as a tea or grated into vegetable juice.
Boswellia: This herb contains specific active anti-inflammatory
ingredients, referred to as boswellic acids that animal studies
have shown significantly reduce inflammation. This is one of my
personal favorites as I have seen it work well with many of my
rheumatoid arthritis patients
Fish Oils: The omega-3 fats EPA and DHA found in fish oil have
been found, by many animal and clinical studies, to have
anti-inflammatory properties that reduce joint inflammation and
promote joint lubrication.
Those of you who read the newsletter regularly know that I'm a
fan of Carlson's brand fish oil and cod liver oil as I have seen
clear and often substantial improvements in my patients who use
it. It has shown particularly positive benefits in those with
rheumatoid arthritis.
Bromelain: This enzyme, found in pineapples, is a natural
anti-inflammatory. It can be taken in supplement form, but
eating fresh pineapple may also be helpful.
Cetyl Myristoleate (CMO): This oil, found in fish and dairy
butter, acts as a "joint lubricant" and an anti-inflammatory.
The delicious raw butter we carry from organic pastures contains
"Wulzen anti-stiffness factor." This factor has been found to be
highly effective in reversing arthritis and protects against
calcification of joints.
Evening Primrose, Black Currant and Borage Oils: These contain
the essential fatty acid gamma linolenic acid (GLA), which is
useful for treating arthritic pain. I personally prefer the use
of GLA supplements from evening primrose oil, but borage oil
contains a higher concentration of GLA, which means you need
fewer capsules, and it tends to be less expensive.
Cayenne Cream: Also called capsaicin cream, this spice comes
from dried hot peppers. It alleviates pain by depleting the
body's supply of substance P, a chemical component of nerve
cells that transmits pain signals to the brain.